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IPBS 801 FUNDAMENTALS OF BIOMOLECULES 3 Credit Hours

Introduction to concepts in the biochemistry of macromolecules, including the structure and function of proteins and nucleic acids, sugars and lipids. Basic material related to acid-base, buffers, intermolecular interactions, and enzymology lead to discussion of synthesis, folding, and degradation of proteins. Basic information on the structure of DNA and RNA leads to discussion of the mechanisms of replication, repair, recombination, restriction, transcription-translation and regulation of chromatin structure/gene expression.

Prerequisite: all IGPBS students or Pharm Sci PhD students Graduate students from certain programs

Typically Offered: FALL

IPBS 803 FUNDAMENTALS OF RECEPTORS & CELL SIGNALING 2 Credit Hours

Introduction to fundamental concepts of receptor-mediated regulation of cell function through signal transduction networks.

Typically Offered: FALL

IPBS 804 BIOSCIENCE ENTREPRENEURSHIP 2 Credit Hours

To move from discovery to commercialized applications, the entrepreneur must have a wide variety of skills to address a variety of economic, legal and scientific requirements. The purpose of this course is to define these essential skills and provide a background of the requirements that are necessary to commercialize new inventions.

Typically Offered: FALL

IPBS 805 FUNDAMENTALS OF CELLULAR PROCESSES 3 Credit Hours

In a flipped-classroom setting, this course provides training in scientific critical thinking and experimentation through a mixture of asynchronous learning activities, in-class small group discussions, and workshops, focusing on fundamental cellular processes within three learning modules. Module 1: DNA as a Hard Drive - DNA replication, repair, transcription, and related aberrancies disease. Module 2: RNA and Proteins as Working Memory and System Output - post-transcriptional processing, RNA translation, protein sequences, post-translational modifications, and protein turnover. Module 3: Cells Sensing Responding to Their Environment - signaling events triggered by ligand-receptor interactions, responses of excitable cells, and cellular metabolism. The course focus is on learning these cellular processes through experimental design and data analysis to enhance critical thinking.

Instructor: Course Director: Matthew C. Zimmerman, Ph.D.; Professor; Dept of Cellular Integrative Physiology; Director, Interdisciplinary Graduate Program in Biomedical Sciences (IGPBS); Email: mczimmerman@unmc.edu. Course Module 1 Director: Andrew Dudley, Ph.D.; Associate Professor; Dept of Genetics, Cell Biology Anatomy; Email: andrew.dudley@unmc.edu. Course Module 2 Director: Kate Hyde, Ph.D.; Associate Professor; Dept of Biochemistry Molecular Biology; Email: kate.hyde@unmc.edu. Couse Module 3 Director: Keshore Bidasee, Ph.D.; Professor; Dept of Pharmacology Experimental Neuroscience; Email: kbidasee@unmc.edu. Additional instructors include UNMC graduate faculty who will provide asynchronous learning materials (e.g., eModules, narrated lectures, and/or readings) and will moderate the Thursday in-class small group discussions and workshops.

Typically Offered: FALL

Capacity: 60

IPBS 850 CRITICAL ANALYSIS OF THE SCIENTIFIC LITERATURE 1 Credit Hour

To provide a course that will help incoming IGPBS students who have not yet committed to a doctoral program to develop a strong foundation in how to read and critically analyze the primary literature.

Prerequisite:  Class for IGPBS students only

Typically Offered: FALL

IPBS 860 SUCCESS SKILLS FOR GRADUATE STUDENTS 1 Credit Hour

This course is designed to prepare first-year students in biomedical research-focused graduate programs to successfully navigate their graduate training. Students will learn basic skills in literature review, rigor / reproducibility, responsibilities regarding data management and curation, problem-solving, communication, professionalism / leadership in science, and basic technical writing.

Prerequisite:  For students not enrolled in IGPBS or one of its programs, permission from the course director is required.

Instructor: Dr. Lisa Rucks, Professor, Department of Pathology, Microbiology, and Immunology, College of Medicine, Office: Durham Research Center (DRC)2-5028, Phone: 402-559-0750, Email: lisa.rucks@unmc.edu. Dr. Erika Boesen, Associate Professor, Department of Cellular Integrative Physiology, College of Medicine, Office: DRC1-6044, Phone: 402-559-6055, Email: erika.boesen@unmc.edu. Additional faculty who are experts in specific content will be determined as needed.

Typically Offered: FALL

Capacity: 60

IPBS 896 RESEARCH OTHER THAN THESIS 1-9 Credit Hours

Student research that is clearly distinct from ongoing or planned thesis/dissertation work, or research/lab rotations preformed prior to selecting a permanent advisor or supervisor.

Prerequisite:  must be IGPBS student

Typically Offered: FALL/SP/SU

IPBS 970 SEMINAR 1 Credit Hour

Attendance at weekly seminars offered by the department/program, or other activities specific to the degree program (contact the program director for more information).

Prerequisite:  Must be IGPBS student to register

Typically Offered: FALL/SP/SU